Studies on the Biosynthesis of Rabbit Fibrinogen By VALDA
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چکیده
many advantages. It was first shown by Miller, Bly & Bale (1954) that fibrinogen was synthesized in the dog solely in the liver, a finding recently substantiated by Kukral, Kerth, Pancner, Cromer & Henegar (1961). Moreover, the rate of synthesis of fibrinogen as deduced from its metabolic turnover is probably greater than that of any of the other groups of serum proteins. For example, Cohen, Holloway, Matthews & McFarlane (1956) estimated that the half-life of fibrinogen in the rabbit is 52-85 hr., compared with 190 hr. for serum albumin. From structural considerations fibrinogen is also
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تاریخ انتشار 2005